| Ponce de Leon is a town in Holmes County. It has an area of 5 square miles, of which .20% is water. Ponce de Leon has a population of 462, as of 2004. The median age was 40 years, and for every 100 females there were 94.5 males. The median income for a household in Ponce de Leon was $25,521, and for a family it was #33,250. The per capita income for the town was $14,673. |